Salmon Thrombin

Description
Plasma protein from the blood of farmed S. salar

Product Background
Salmon thrombin is a unique hemostatic and analgesic. In animal studies, it provides significant and sustained relief from post-surgical, bone, and burn pain.

Salmon thrombin and fibrinogen form fibrin gels that have demonstrated remarkable properties in stem cell culture and neuron survival and growth.

  • Salmon fibrin gels represent the optimal extracellular matrix for neuronal and stem cell culture.
  • Salmon fibrin gels also have properties superior to mammalian gels in an in vitro angiogenesis model. The salmon gels were 60-188% more efficient than human fibrin gels supporting growth of human endothelial cells. These results indicate that salmon fibrin may be attractive alternate ECM for support of microvascular network formation.
  • Salmon fibrinogen and thrombin can be used at < room temperature.
  • Soft salmon fibrin gels have been shown to promote selection and growth of tumorigenic cells.

Regenerative Medicine

  • Spinal Cord Injury
  • Neural cell regrowth
  • PainĀ  studies
  • Stem cell research
  • Cancer cell research

Benefits:

  • Superior performance of fibrin gels- demonstrated superiority to Matrigel as an extracellular matrix for stem cells and neuronal cell growth.
  • Safety from mammalian pathogens
  • Ease of rehydration & improved thermal properties.
  • Unique properties